Comparative Study of Glyceryl Trinitrate Ointment versus Lateral Internal Sphincterotomy in Management of Chronic Anal Fissure

Comparative study of lateral internal sphincterotomy versus local 0.2% glyceryl trinitrate ointment for the treatment of chronic anal fissure.

The gold standard surgical treatment of chronic anal fissure is lateral internal sphincterotomy which lowers the resting anal pressure and effectively heals the majority of fissures. Local application of 0.2% glyceryl trinitrate ointment has been used as an agent for chemical sphincterotomy, causing temporary alleviation of sphincter spasm and allowing the fissure to heal without compromising t...

Diltiazem (2%) versus glyceryl trinitrate cream (0.2%) in the management of chronic anal fissure.

OBJECTIVE To assess and compare the effectiveness of topical 0.2% glycerl trinitrate (GTN) and topical 2% diltiazem (DTZ), in the management of chronic anal fissure. STUDY DESIGN Comparative, descriptive study. PLACE AND DURATION OF STUDY Department of Surgery, Liaquat University of Medical and Health Sciences, Jamshoro/Hyderabad from September 2004 to August 2005. METHODOLOGY Patients wi...

Study of operated patients of lateral internal anal sphincterotomy for chronic anal fissure.

INTRODUCTION Anal fissure causes significant morbidity in the population. It is proposed that elevated sphincter pressures may cause ischaemia of the anal lining and this may be responsible for the pain of anal fissures and their failure to heal. When pharmacologic therapy fails or fissures recur frequently, lateral internal sphincterotomy is the surgical treatment of choice. MATERIAL AND MET...

Topical Diltiazem versus topical Glyceryl trinitrate (GTN) in the treatment of chronic anal fissure: Prospective study

Presidential address. Lateral subcutaneous internal anal sphincterotomy for anal fissure.

AN ANAL FISSURE is ai1 ulcer of t h e a n a l canal which may extend from the anal verge to the dentate line. It is usually exquisitely painful, so the best treatment is that which is the most expedient but also provides negli#ble recurrence and minimal disability of anal function. Lateral subcutaneous internal anal sphincterotomy best fulfills these criteria and we strongly recommend it as the...